Home : Publications : Biography : Research : Alumni : Contact

Publications 1996-2000
-
Rondard, P. & Bedouelle, H. (2000). Mutational scanning of a hairpin loop in tryptophan synthase alpha-subunit, implicated in allostery and substrate channeling. Biol. Chem. 381, 1185-1193.
Full text [PDF]

Guez, V., Nar, S., Chaffotte, A. & Bedouelle, H. (2000). The anticodon-binding domain of tyrosyl-tRNA synthetase: state of folding and origin of the crystallographic disorder. Biochemistry, 39, 1739-1747.
Full text [PDF]

Pintar, A., Guez, V., Castagne, C., Bedouelle, H. & Delepierre, M. (1999). Secondary structure of the C-terminal domain of the tyrosyl-transfer RNA synthetase from Bacillus stearothermophilus: a novel type of anticodon binding domain? FEBS Lett. 446, 81-85.
Full text [PDF]

Jermutus, L., Guez, V. & Bedouelle, H. (1999). Disordered C-terminal domain of tyrosyl-tRNA synthetase: secondary structure predictions. Biochimie, 81, 235-244.
Full text [PDF]

England, P., Nageotte, R., Renard, M., Page, A. L. & Bedouelle, H. (1999). Functional characterisation of the somatic hypermutation process leading to antibody D1.3, a high affinity antibody directed against lysozyme. J. Immunol. 162, 2129-2136.
Full text [PDF]

Park, Y. C., Guez, V. & Bedouelle, H. (1999). Experimental evolution of a dense cluster of residues in tyrosyl-tRNA synthetase: quantitative effects on activity, stability and dimerization. J. Mol. Biol. 286, 563-577.
Full text [PDF]

Rondard, P. & Bedouelle, H. (1998). A mutational approach shows similar mechanisms of recognition for the isolated and integrated versions of a protein epitope. J. Biol. Chem. 273, 34753-34759.
Full text [PDF]

Guermonprez, P., England, P., Bedouelle, H. & Leclerc, C. (1998). The rate of dissociation between antibody and antigen determines the efficiency of antibody-mediated antigen presentation to T cells. J. Immunol. 161, 4542-4548.
Full text [PDF]

Park, Y. C. & Bedouelle, H. (1998). Dimeric tyrosyl-tRNA synthetase from Bacillus stearothermophilus unfolds through a monomeric intermediate: a quantitative analysis under equilibrium conditions. J. Biol. Chem. 273, 18052-18059.
Full text [PDF]

Bregegere, F., England, P., Djavadi-Ohaniance, L. & Bedouelle, H. (1997). Recognition of E.coli tryptophan synthase by single-chain Fv fragments: comparison of PCR-cloning variants with the parental antibodies. J. Mol. Recognition, 10, 169-181.
Full text [PDF]

Rondard, P., Goldberg, M.E. & Bedouelle, H. (1997). Mutational analysis of an antigenic peptide shows recognition in a loop conformation. Biochemistry, 36, 8962-8968.
Full text [PDF]

Rondard, P., Bregegere, F., Lecroisey, A., Delepierre, M. & Bedouelle, H. (1997). Conformational and functional properties of an undecapeptide epitope fused with the C-terminal end of the maltose binding protein. Biochemistry, 36, 8954-8961
Full text [PDF]

England, P., Bregegere, F. & Bedouelle, H. (1997). Energetic and kinetic contributions of contact residues of antibody D1.3 in the interaction with lysozyme. Biochemistry, 36, 164-172.
Full text [PDF]

Blondel, A., Nageotte, R. & Bedouelle, H. (1996). Destabilizing interactions between the partners of a bifunctional fusion protein. Protein Engng, 9, 231-238.
Full text [PDF]

Guez-Ivanier, V. & Bedouelle, H. (1996). Disordered C-terminal domain of tyrosyl transfer-RNA synthetase: evidence for a folded state. J. Mol. Biol. 255, 110-120.
Full text [PDF]
-